The Bison are a member of the NCAA FCS Missouri Valley Football Conference, which they joined in 2008. Previously the Bison were a member of the Great West Football Conference from 2004 to 2007 after the school moved up from NCAA Division II.
The Bison play their home games at the Fargodome in Fargo and are currently coached by Matt Entz.
North Dakota State had won five consecutive NCAA FCS national championships, beginning in 2011, and had a 22-game postseason winning streak before losing to James Madison in the 2016 FCS semifinals.
- 2008-present - Missouri Valley Football Conference (NCAA FCS)
- 2004-2007 - Great West Football Conference (NCAA FCS/1-AA)
- 1922-2003 - North Central Conference (NCAA Division II)