Head Coach: Bill Conley (12th season)
Stadium: Panther Stadium, Columbus, OH
Record:
Previous: 2020
Next: 2022
Schedule/Results
| Date | Opponent | Result | Score | Record |
|---|---|---|---|---|
| 9/2 (Thu) | Shepherd | L | 30-35 | 0-1 |
| 9/11 | Virginia State | W | 10-7 | 1-1 |
| 9/18 | @ William Jewell | W | 35-25 | 2-1 |
| 9/25 | @ Indianapolis | W | 19-16 (2OT) | 3-1 |
| 10/2 | @ Kentucky Wesleyan | W | 32-30 | 4-1 |
| 10/9 | @ Ashland | W | 34-24 | 5-1 |
| 10/16 | Findlay | L | 14-21 (OT) | 5-2 |
| 10/23 | Walsh | W | 56-17 | 6-2 |
| 10/30 | @ Tiffin | L | 21-34 | 6-3 |
| 11/6 | Lake Erie | W | 31-0 | 7-3 |
| 11/13 | @ Hillsdale | L | 17-21 | 7-4 |