Head Coach: Mike Gundy (2nd season)
Stadium: Boone Pickens Stadium, Stillwater, OK
Record: 7-6
Previous: 2005
Next: 2007
Schedule/Results[]
| Date | Opponent | Result | Score | Record |
|---|---|---|---|---|
| 9/2 | Missouri State | W | 52-10 | 1-0 |
| 9/9 | @ Arkansas State | W | 35-7 | 2-0 |
| 9/16 | Florida Atlantic | W | 48-8 | 3-0 |
| 9/23 | @ Houston | L | 25-34 | 3-1 |
| 10/7 | @ Kansas State | L | 27-31 | 3-2 |
| 10/14 | @ Kansas | W | 42-32 | 4-2 |
| 10/21 | Texas A&M | L | 33-34 (OT) | 4-3 |
| 10/28 | Nebraska | W | 41-29 | 5-3 |
| 11/4 | @ Texas | L | 10-36 | 5-4 |
| 11/11 | Baylor | W | 66-24 | 6-4 |
| 11/18 | @ Texas Tech | L | 24-30 | 6-5 |
| 11/25 | Oklahoma | L | 21-27 | 6-6 |
| Independence Bowl (@ Independence Stadium, Shreveport, LA) | ||||
| 12/28 | Alabama | W | 34-31 | 7-6 |