2006 Ohio State Buckeyes
Head Coach: Jim Tressel (6th season)
Stadium: Ohio Stadium, Columbus, OH
Record: 12-1 (8-0 Big Ten)
Previous: 2005
Next: 2007
Schedule/Results[]
| Date | Opponent | Result | Score | Record |
| 9/2 | Northern Illinois | W | 35-12 | 1-0 |
| 9/9 | at Texas | W | 24-7 | 2-0 |
| 9/16 | Cincinnati | W | 37-7 | 3-0 |
| 9/23 | Penn State | W | 28-6 | 4-0 (1-0) |
| 9/30 | at Iowa | W | 38-17 | 5-0 (2-0) |
| 10/7 | Bowling Green | W | 35-7 | 6-0 (2-0) |
| 10/14 | at Michigan State | W | 38-7 | 7-0 (3-0) |
| 10/21 | Indiana | W | 44-3 | 8-0 (4-0) |
| 10/28 | Minnesota | W | 44-0 | 9-0 (5-0) |
| 11/4 | at Illinois | W | 17-10 | 10-0 (6-0) |
| 11/11 | at Northwestern | W | 54-10 | 11-0 (7-0) |
| 11/18 | Michigan | W | 42-39 | 12-0 (8-0) |
| BCS Championship (@ University of Phoenix Stadium, Glendale, AZ) | ||||
| 1/8 (Mon) | Florida | L | 14-41 | 12-1 (8-0) |
Notes[]
Ohio State QB Troy Smith won the 2006 Heisman Trophy.