1999 Ohio State Buckeyes
Head Coach: John Cooper (12th season)
Stadium: Ohio Stadium, Columbus, OH
Record: 6-6 (3-5 Big Ten)
Previous: 1998
Next: 2000
Schedule/Results[]
| Date | Opponent | Result | Score | Record |
| 8/29 (Sun) | Miami (FL) (1) | L | 12-23 | 0-1 |
| 9/11 | UCLA | W | 42-20 | 1-1 |
| 9/18 | Ohio | W | 40-16 | 2-1 |
| 9/25 | Cincinnati | W | 34-20 | 3-1 |
| 10/2 | Wisconsin | L | 17-42 | 3-2 (0-1) |
| 10/9 | Purdue | W | 25-22 | 4-2 (1-1) |
| 10/16 | at Penn State | L | 10-23 | 4-3 (1-2) |
| 10/23 | at Minnesota | W | 20-17 | 5-3 (2-2) |
| 10/30 | Iowa | W | 41-11 | 6-3 (3-2) |
| 11/6 | at Michigan State | L | 7-23 | 6-4 (3-3) |
| 11/13 | Illinois | L | 20-46 | 6-5 (3-4) |
| 11/20 | at Michigan | L | 17-24 | 6-6 (3-5) |
- (1) - @ Giants Stadium, East Rutherford, NJ