2006 Hamilton Tiger-Cats

The 2006 Hamilton Tiger-Cats season was the 49th season for the team in the Canadian Football League and their 57th overall. The Tiger-Cats finished in 4th place in the East Division with a 4–14–0 record and missed the playoffs. Head coach Greg Marshall was fired after the first four games of the season and Ron Lancaster took over as interim head coach for the remaining 14 games.

2006 CFL All-Stars

 * No players selected

Eastern Division All-Star Selections

 * Tay Cody - Defensive Back