2013 San Francisco 49ers

The  San Francisco 49ers season will be the franchise's upcoming 64th season in the National Football League, their 68th overall and the third under the head coach/general manager tandem of Jim Harbaugh and Trent Baalke. It will also be the 49ers' final season playing their home games at Candlestick Park, as the team will move into a new stadium in Santa Clara in 2014.

2013 NFL Draft

 * Notes
 * The team acquired an additional third-round selection (No. 74 overall) as part of a trade that sent a 2012 fourth-round selection to the Carolina Panthers.
 * The team acquired an additional fifth-round selection as part of a trade that sent a 2012 third-round selection to the Indianapolis Colts.
 * The team acquired an additional sixth-round selection as part of a trade that sent a 2012 fourth-round selection to the Miami Dolphins.
 * The team acquired an additional seventh-round selection in a trade that sent safety Taylor Mays to the Cincinnati Bengals.
 * Exact numbers of the selections from rounds 4–7 will be determined when compensatory selections are awarded at the NFL's annual owners' meetings in late-March.

Preseason
The 49ers' preseason opponents and schedule will be announced in the spring.

2013 opponents
On October 11, 2012, the NFL announced that the 49ers will play the Jacksonville Jaguars in the International Series at Wembley Stadium in London, England. The game will occur during Week 8 on Sunday, October 27, at 10:00 a.m. PDT (5:00 p.m. GMT), and will be aired by Fox in the United States. The Jaguars will be the designated home team for this game, and both teams will have their bye the following week.

The remainder of the 49ers' 2013 schedule will be finalized and announced in April. Listed below are the 49ers' opponents for :