2012 Indianapolis Colts

The  Indianapolis Colts season will be the franchise's upcoming 60th season in the National Football league and the 29th in Indianapolis.

On January 2, 2012, one day after the final game of the 2011 season, Colts owner Jim Irsay fired team Vice Chairman Bill Polian (who had been the team's general manager since 1998) and his son, team Vice President and general manager Chris Polian. Nine days later (January 11), Ryan Grigson was named the new general manager.

Irsay stated that the fate of head coach Jim Caldwell was still under review.

2012 draft class

 * Note: Exact numbers of the selections from rounds 4–7 will be determined later in the spring after compensatory selections are awarded.

Preseason
The Colts' preseason opponents and schedule will be announced in the spring.

2012 Opponents
Listed below are the Colts' opponents for 2012. Exact dates and times will be announced in the spring.